| abstract |
THE INVENTION RELATES TO A PROCESS FOR PURIFYING A PRODUCT OF GENETIC EXPRESSION OBTAINED BY RECOMBINANT DNA TECHNIQUE. ACCORDING TO THE INVENTION, IT INCLUDES A SPECIFIC SEQUENCE OF STEPS INCLUDING A SILICA GEL ADSORPTION TREATMENT, AN ACTIVE CARBON ADSORPTION TREATMENT, CENTRIFUGATION AT LEAST DOUBLE DENSITY AND CENTRIFUGATION AT GRADIENT DENSITY A. AT LEAST DOUBLE BALANCE. THE PRESENT INVENTION APPLIES IN PARTICULAR TO THE REMOVAL OF AN ALLERGEN FROM GENETIC EXPRESSION PRODUCTS THUS CONTAMINATED, ALLOWING THE PRODUCTION, ON A LARGE SCALE, OF VERY PURIFIED GENETIC EXPRESSION PRODUCTS. |