| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-826 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 |
| filingDate |
1985-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eeb60836bc52402e9d3243824e01110
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16d6844aacb24151cdf4e5e71a3f8acc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97f968b79766a3458a520b5bb6ed3dcf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2e7c6b67fef3b710d842b956eef07f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91211055053ebce0520cc8c14642bb23 |
| publicationDate |
1985-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0155007-A2 |
| titleOfInvention |
Method for purification of HBs antigen |
| abstract |
Industrially useful method for the purification of HBs antigen produced by a recombinant organism being capable of producing HBs antigen which is prepared by means of DNA recombination technique, which comprises subjecting an HBs antigen-containing material produced by a recombinant organism to an adsorption chromatography with a silica, optionally followed by a gel filtration and further an adsorption chromatography with a hydroxyapatite, and then eluting the HBs antigen, preferably, with a buffer having pH 9 or more containing urea. The purification method can give a highly pure HBs antigen suitable for the preparation of hepatitis B vaccine in a large scale from recombinant organisms prepared by DNA recombination techniques. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0310178-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01128935-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0337492-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2600341-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0204680-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2602681-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5004688-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0204680-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3726879-A1 |
| priorityDate |
1984-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |