| abstract |
FARNESYLACETIC ACID AMIDE-TYPE COMPOUNDS OF THE GENERAL FORMULA: (CF DRAWING IN BOPI) IN WHICH A IS AN ALKYLENE RADICAL OF AT LEAST 2 CARBON ATOMS, R IS A HYDROGEN ATOM OR A LOWER ALKYL RADICAL, AND R AND R ARE EACH, INDEPENDENTLY, A HYDROGEN ATOM, A RADICAL ALKYL, CYCLOALKYL, ALKENYL, ARYL OR ARALKYL, OR ONE OF R AND R IS A GROUP THAT FORM, WITH A, A PIPERIDINE CORE CONTAINING AS A CONSTITUENT THE NITROGEN ATOM LOCATED BETWEEN THEM, OR AGAIN R AND R, IN COMBINATION, REPRESENT A GROUP WHICH, WITH THE NITROGEN ATOM TO WHICH THEY ARE BOUND, A PIPERIDINE, PYRROLIDINE OR PIPERAZINE CORE. THESE COMPOUNDS, AS WELL AS THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, ARE USEFUL AS ANTIULCEROGENS AND ANTIBACTERIAL AGENTS. |