| abstract |
An alkylenediamine derivative or a salt thereof expressed by the followingnformula 1:n nwherein each of R 1 and R 2 represents a lower alkyl group, and W represents angroup expressed by any of the following formulas 2 to 4;n n n nwhereinn R 3 is an alkenyl group; R 4 is a lower alkyl group, a lower alkoxy group, or a halogen atom; X is a group expressed by -O-, -S-, or -N(R 5 )-, while R 5 isnhydrogen atom, a lower alkyl group, or an alkenyl group; Y is carbon or nitrogen atom; m is an integer of 1 to 3; n is an integer of 0 to 2; R 6 is a lower alkyl group; R 7 is hydroxy or benzyloxy group; R 8 is a lower alkyl, a lower alkoxy, a piperidinoalkyl, a substitutedncarbamoyl, or a substituted amino group; and l is 1 or 2. n The alkylenediamine derivative has an anti- ulcer effect or an antibacterialnactivity against Helicobacter pyroli, and has also high safety to be available fornprevention or cure of ulcers. |