abstract |
A procedure to obtainnclarithromycinn n n The present invention describes obtainingnErythromycin A derivatives, which serve as intermediates fornobtaining ofn6-O-methyl-erythromycinnA, called clarithromycin, particularly, through thenobtaining and employing 9-O-ariln9-oxime derivatives of erythromycin A and thensubsequent purification of the crude product through the formationnof a thiocyanate salt. |