| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5095f60dee8e6d7c3faa7cca7b58c08 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2001-302 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-536
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532 |
| filingDate |
2016-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c5115ac793e5bd691dfd2c5a499f559
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e707da7476f3a0400ea4e155d1bb357b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdff633e23d52940804bdf2939183e4c |
| publicationDate |
2018-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3336546-A1 |
| titleOfInvention |
Reversible cell labelling with conjugates having two releasable binding sites |
| abstract |
The invention is directed to a Method for detecting a target moiety in a sample of biological specimens by: na) providing at least one conjugate with the general formula (I) n n A n - P - B m - C q -X o (I) n nwith nA: nantigen recognizing moiety; nP: nenzymatically degradable spacer; nB: nfirst binding moiety nC nsecond binding moiety nX: ndetection moiety; nn, m, q, o nintegers between 1 and 100, nwherein B and C are non-covalently bound to each other and A and B are covalently bound to P nb) labelling the target moiety recognized by the antigen recognizing moiety A with at least one conjugate nc) detecting the labelled target moiety via detecting moiety X nd) cleaving C q -X o by disrupting the non-covalent bond between B m and Cq from the labelled target moiety ne) cleaving the binding moiety B m from the labelled target moiety by enzymatically degrading spacer P. n The method is useful to identify target moieties on the biological specimens. The biological specimens detected by the conjugate can be subsequently removed from the sample. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021047804-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022043023-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021164959-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020239866-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020216439-A1 |
| priorityDate |
2016-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |