| abstract |
The present invention provides a cationic lipid, which allow nucleic acids to be easily introduced into cells, represented by formula (I)n n(wherein: nR 1 and R 2 are, the same or different, each (Z)-pentadecenyl, (Z)-hexadecenyl or ( Z )-heptadecenyl, etc, na and b are, the same or different, each 0 to 3, nm is 1, nthe dotted line is a single bond or absent, nX 1 and X 2 are hydrogen atoms, or are combined together to form a single bond or alkylene, nX 4 is absent or is alkylene, etc nX 3 is absent or is alkyl, etc, nY is absent or anion, nL 3 is a single bond, -CO-O- or -O-CO- nR 3 is hydrogen atoms, alkyl, etc, nL 1 and L 2 are -0-, -CO-O- or -O-CO-) and the like. |