| abstract |
Transdermal therapeutic system comprising a cover layer, an adhesive matrix containing fentanyl as active ingredient and a peelable protective layer, characterized by an acrylate copolymer adhesive matrix which is free of penetration accelerators, the adhesive matrix being selected from the groups of basic acrylate copolymer, in particular acrylate copolymer with hydroxyethyl acrylate units, and with an organic titanium compound as crosslinker and basic acrylate copolymer with vinyl acetate units and free of crosslinking agents, in particular acrylate copolymer with hydroxyethyl acrylate units and vinyl acetate units. |