| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dded61bd89f99900518597c0958b9a9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 |
| filingDate |
2011-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dd429b53fddb930beab3b5495f062e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b8594f544197afa061b4ef49731b1d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5d84187dad4f907a07d1b2c138b78a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2f1cd0b8a62d1546bbb7aeb0227b6e9 |
| publicationDate |
2012-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2404926-A1 |
| titleOfInvention |
Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-adenine |
| abstract |
A process for making clofarabine comprising: fluorinating a compound of formula VIIn nwherein each R 4 is independently a hydroxy protecting group, OR 6 is a leaving group, with a fluorinating agent in the presence of guanidine carbonate to give a compound of formula VIII:n nwherein R 4 is as defined above; and deprotecting the compound of formula VIII to give the clofarabine. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017513884-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160141764-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2937420-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101868728-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015162175-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10030043-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2663584-C2 |
| priorityDate |
2010-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |