| abstract |
The present invention is directed to a rhenium complex of general Formula (I) or a pharmaceutically acceptable salt or solvate thereof wherein X is chosen from S Se or Te; Y is NH, O or S or is a methylene group; Z is halogen; m = 0,1 , or 2 and p = 0,1 , or 2, provided that m and p are both different from zero when Y is NH, O or S; n = 3; R 1 is a phenyl group or a group of general Formula (CH 2 ) q -COOH wherein q = 1 or 2, a pharmaceutical composition comprising a therapeutically effective amount of at least one of such rhenium complex, a method for preparing said rhenium complex and a method for treating a proliferative growth related-disorder using a therapeutically effective amount of at least one of said rhenium complex. Also claimed are compounds of formula (II). |