Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 |
filingDate |
2006-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8da3f83530c8836780950c3da1066a29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07aa4c8cdfd7fcfb91115a6110a092f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d724031ef02623f99ff0d0804598b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b2575fb8eb43a2567bdc0f11783a4f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de09bf167d16a691f63d26a992d0261b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4821342d612e35406478646ac0b71d56 |
publicationDate |
2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2292653-A1 |
titleOfInvention |
Novel insulin derivatives |
abstract |
The present invention is related to insulin derivatives having a side chain attached either to the α-amino group of the N-terminal amino acid residue of B chain or to an ε-amino group of a Lys residue present in the B chain of the parent insulin molecule via an amide bond which side chain comprises one or more residues of ethylenglycol, propyleneglycol and/or butyleneglycol containing independently at each termini a group selected from -NH 2 and -COOH; a fatty diacid moiety with 4 to 22 carbon atoms, at least one free carboxylic acid group or a group which is negatively charged at neutral pH; and possible linkers which link the individual components in the side chain together via amide or ether bonds, said linkers optionally comprising a free carboxylic acid group. |
priorityDate |
2005-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |