http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2264188-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8adaddc602ad7cb7f9e2d550681bb36d |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6848 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2004-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c61b589e1336195d4c79d8fa8025358f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22fa96a0ad16dcffc0b8b1323b0543b6 |
publicationDate | 2010-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2264188-A1 |
titleOfInvention | Methods and compositions for whole genome amplification and genotyping |
abstract | There is disclosed a method for indicating the presence of single nucleotide polymorphisms (SNPs) of interest in typable loci of a genome, comprising the steps of: n(a) representationally amplifying a native genome to obtain a representative population of genome fragments comprising said typable loci; n(b) contacting said fragments with an array of different immobilized nucleic acid probes under conditions wherein probe-fragment hybrids are formed, nwherein said fragments have a concentration of at least 1 µg/ul of DNA and nwherein said immobilized nucleic acid probes comprise a region that is complementary to typable loci of a genome; n(c) contacting said probe-fragment hybrids with a modification enzyme, nwhereby if the typable locus of a fragment contains a SNP of interest, a detection moiety is attached to the hybridized probe; and n(d) detecting the probe, thereby indicating the presence of said single nucleotide polymorphisms of interest at typable loci of said genome. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10415083-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3428290-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014018093-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10870099-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4071253-A1 |
priorityDate | 2003-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 305.