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publicationDate 2010-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2202306-A1
titleOfInvention Genetically engineered blood coagulation factor x having no sugar chain, and method for production thereof
abstract A Factor X (hereinafter referred to as "FX") with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
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