| abstract |
Disclosed is a compound useful as an inhibitor of 11β-hydroxysteroid dehydrogenase type 1. nA compound represented by the formula:n na pharmaceutically acceptable salt or solvate thereof, nwherein nR 1 is a group of the formula: -C(=O)NR 4 R 5 , n(wherein R 4 and R 5 are each independently, hydrogen, optionally substituted alkyl or the like) or na group of the formula: -NR 6 C(=O)R 7 , n(wherein R 6 and R 7 are each independently, hydrogen, optionally substituted alkyl or the like), nX and Y are each independently -0- or the like, nZ is a bond or the like, nR 2 is optionally substituted alkyl, optionally substituted alkenyl or the like, nR 3 is optionally substituted alkyl, optionally substituted alkenyl or the like. |