Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-164 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y601-01002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-43 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-53 |
filingDate |
2006-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c704686ae7d3e3aa7df0bb3d52df3033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6b429f2cb1355f7f25c20567a04ed31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5331affa1039960f8f4e3b0848b6b975 |
publicationDate |
2008-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1902725-A2 |
titleOfInvention |
Revascularization of ischemic retinal tissue |
abstract |
The present invention provides a treatment for promoting beneficial physiological revascularization of ischemic retinal tissue. The treatment comprises administering to a mammal suffering from a retinal vascular ischemia a therapeutically effective amount of an angiostatic fragment of tryptophanyl-tRNA synthetase (TrpRS), thereby simultaneously inhibiting pathological neovascularization while promoting beneficial physiological revascularization of damaged areas of the retina. In a preferred embodiment, the angiostatic fragment of TrpRS is T2-TrpRS or T2-TrpRS-GD. Preferably, the mammal is a human patient suffering from retinal ischemia. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2452442-C1 |
priorityDate |
2005-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |