| abstract |
The present invention provides nucleotide sequences which can be used for construction of modified promoters of the genes involved in the valine, leucine and isoleucine biosynthesis pathways (ilvA, ilvB, ilvD, ilvE and leuA), the mutated promoters themselves, the vector for construction of the mutations in the chromosome, the strains carrying the modified promoters and a process for the fermentative production of branched-chain amino acids using these modified promoters in specific hosts in which genes are expressed from these promoters. |