| abstract |
The present invention provides a compoundnrepresented by the formula:n nwherein R 1 is an optionally substituted 5-memberednheterocyclic group; X, Y and V are the same or differentnand each is a bond, an oxygen atom, a sulfur atom andnthe like; Q is a divalent hydrocarbon group having 1 ton20 carbon atoms; ring A is an aromatic ring optionallynfurther having 1 to 3 substituents; Z is -(CH 2 ) n -Z 1 - orn-Z 1 -(CH 2 ) n - (n is an integer of 0 to 8, Z 1 is a bond, annoxygen atom, a sulfur atom and the like); ring B is annitrogen-containing heterocycle optionally furthernhaving 1 to 3 substituents; W is a bond or a divalentnhydrocarbon group having 1 to 20 carbon atoms; R 2 is anhydrogen atom, a cyano group, -PO(OR 9 )(OR 10 ) (R 9 and R 10 nare the same or different and each is a hydrogen atom ornan optionally substituted hydrocarbon group, and R 9 andnR 10 are optionally bonded to form an optionallynsubstituted ring) and the like, or a salt thereof, whichnhas a superior adipose tissue weight decreasing action,na hypoglycemic action and a hypolipidemic action, andnwhich is useful as an agent for the prophylaxis orntreatment of obesity, diabetes mellitus, hyperlipidemia,nimpaired glucose tolerance, hypertension and the like. |