abstract |
The present invention relates to a pharmaceutical preparation for the improvedntreatment of blood-clotting disorders containing one or several factor VIII derivednpeptides which increases the plasma half life of factor VIII. Further, such peptides,ntheir DNA-sequences, their recombinant expression as albumin fusion proteins andnvectors containing such DNA-sequences as well as host cells for such recombinantnexpression vectors and the use of such DNA-sequences in a transfer vector forngene therapy are disclosed. |