http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1438416-A2

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-683
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34
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filingDate 2002-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_269010cc38e85fae584ab50589abcdd2
publicationDate 2004-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1438416-A2
titleOfInvention Assays for dna methylation changes
abstract A new technique to determine the extent of DNA methylation entails generating DNA fragments of a test sample by cleaving at methylation sites that are not methylated while sparing methylation sites in the DNA that are methylated. This approach provides enhanced sensitivity to differences of even a single methylated cytosine, within or outside of a CpG island, and yet it can be employed to ascertain the methylation status of a region of DNA comprising a CpG island, a DNA region comprising one or more CpG-containing islands, or even a large variety of DNA regions.
priorityDate 2001-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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