| abstract |
A system, including methods and apparatus, for microfluidic analysis of annucleic acid target (72) in a nucleic acid mixture (60). The system includes anmethod (40) to preselect (42) the target from the mixture before amplification.nPreselection enriches the mixture (60) for the target (72) by retaining the targetnon a target-selective receptor (78) and then removing unretained non-targetnnucleic acids (74). The preselected target then may be amplified (44) from thenenriched mixture and assayed (46). Devices (62, 114) configured to carry out thenmethod (40) are also disclosed. |