| abstract |
A medicament for preventive and/or therapeutic treatment of a microbialninfection having an activity of eliminating resistance of a microorganism withnacquired resistance to an antimicrobial agent, which comprises as an activeningredient a compound represented by the following general formula (I), anphysiologically acceptable salt thereof, or a hydrate thereof:n nwherein R 1 and R 2 independently represent hydrogen atom, a halogen atom, carboxylngroup and the like; J 1 represents a 5- or 6-membered heteroaromatic ring; W 1 nrepresents -CH=CH-, -C≡C-, -CH 2 CH 2 - and the like; A 1 represents phenylene group,npyridinediyl group, furandiyl group and the like; G 1 represents oxygen atom, carbonylngroup, ethynyl group and the like; p represents an integer of from 0 to 3; G 2 nrepresents phenylene group, furandiyl group, tetrahydrofurandiyl group and the like;nG 3 represents -CH 2 - or single bond; m and n represent an integer of 0 or 1; and Q 1 nrepresents an acidic group. |