| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a933a0dd561e3e50b278738704d5c6e6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4712 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 |
| filingDate |
1993-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02dba3915f4ffd41ff9654255fe8fdc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf600abb9da325b4a36e34ea7b80406a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8158dc89f269e991d4ed2966f9923b26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af7d7c48b2ddfa00bb01d42e9ae548d9 |
| publicationDate |
2010-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1164195-B1 |
| titleOfInvention |
Adeno-associated virus with inverted terminal repeat sequences as promoter |
| abstract |
Described herein are constructions of recombinant DNA comprising modified adeno-associated virus (AAV) DNA sequences capable of functioning as a eukaryotic expression vector for expressing foreign DNA sequences using a novel transcription promoter comprising the termini of AAV DNA. It is shown that expression of a test reporter gene can be obtained from this vector in mammalian cells. It is further shown that this combination of vector and promoter can be used to introduce and express a human gene and correct a genetic defect in human cells resulting from malfunction of the mutant endogenous gene. Further, the vector can be used to correct the genetic defect by expressing a modified version of the human gene consisting of a fusion of part of the said gene and a synthetic sequence contained in the vector. <IMAGE> |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10597660-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10920227-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11759506-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11198873-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10570395-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11027000-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542506-B2 |
| priorityDate |
1992-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |