| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1103b2126f116228c2613f3743dbb90 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65031 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2001-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c156e2f9194327b11cc139ebd8a9284
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4ccefff27dbbf0baefca7cfdcce478f |
| publicationDate |
2002-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1152010-A3 |
| titleOfInvention |
Oligonucleotide labeling reactants and their use |
| abstract |
The invention relates to a novel labeling reactant of formula (I) suitable for labelingnan oligonucleotiden nwherein:n R is a temporary protecting group. A is either a phosphorylating moiety or a solidnsupport tethered to a bridge point Z via a linker arm E. E' is a linker arm between G and Z. G is a bivalent aromatic structure, tethered to two iminodiacetic acid esterngroups N(COOR'") 2 or G is a structure selected from a group consisting ofn nor G is a protected functional group. The invention further concerns a method forndirect attachment of a conjugate group to an oligonucleotide structure enabling thenattachment of a desired number of these groups during chain assembly. The methodncomprises a Mitsonobu alkylation. |
| priorityDate |
2000-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |