abstract |
The present invention is related to piperazine derivatives of carbazole notably for use asnpharmaceutically active compounds, as well as to pharmaceutical formulations containingnsuch piperazine derivatives of carbazole. Said piperazine derivatives of carbazole are efficientnmodulators, in particular inhibitors, of the Bax function and/or activation. The presentninvention is furthermore related to novel piperazine derivatives of carbazole as well asnmethods of their preparation. |