| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45b6e842af2ff4e7797752062b1f9bac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37203dd5349f661f81937465b8f864ea |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2835
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-3094 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 |
| filingDate |
1999-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f22f9f1e27851be4a0d132cb34cc45a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86e0bef9fc37fc5ece8b9426a76775cd |
| publicationDate |
2001-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1065997-A1 |
| titleOfInvention |
Bone xenografts |
| abstract |
The invention provides an article of manufacture comprising a substantially non-immunogenic bone xenograft (X) for implantation into a defect (D) located in a bone portion (10) of a human. The invention further provides methods for preparing a bone xenograft (X) by removing at least a portion of bone from a non-human animal to provide a xenograft (X); washing the xenograft (X) in saline and alcohol; and subjecting the xenograft (X) to at least one of the treatments including exposure to ultraviolet radiation, immersion in alcohol, ozonic, and freeze/thaw cycling. In addition to or in lieu of the above treatments, the methods include a cellular disruption treatment, and digestion of the carbohydrate moieties of the xenograft (X) with a glycosidase followed by treatment for sialylation. |
| priorityDate |
1998-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |