http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0966545-B1

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filingDate 1998-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b943a7bd73fe664b60b9737cf179ce21
publicationDate 2006-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0966545-B1
titleOfInvention Method for typing of minor histocompatibility antigen ha-1
abstract The present invention provides a method for typing of alleles of the Minor Histocompatibility Antigen HA-1 in a sample, the method comprising: a) contacting the genomic polynucleic acids in the sample with at least one pair of primers, whereby the 5'- and/or the 3'-primer of the at least one pair of primers specifically hybridize to target regions comprising polymorphic nucleotides in said alleles, and performing an amplification reaction; b) for each of the at least one pair of primers detecting whether or not in step a) an amplification product is formed; c) inferring from the result of step b) which HA-1 allele is present in the sample. The present invention also provides a method for genomic typing of alleles of the Minor Histocompatibility Antigen HA-1 in a sample and primers and probes for use in the above-mentioned methods. Diagnostic kits enabling the methods are also provided.
priorityDate 1997-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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