http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0884322-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91ce16ac3dbceb38cb5e6983c8c15a5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
filingDate | 1997-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_118cbc45307216e3d2f0a48a34d1670c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d9fc9d67e8ce03f6a6e64cbe32ad9eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d18f193d2408411d62ef3f26f70df29 |
publicationDate | 1998-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0884322-A1 |
titleOfInvention | Processes for the preparation of erythromycin derivatives |
abstract | A method of producing an N-demethyl-N-isopropyl-8,9-anhydroerythromycinnA-6,9-hemiacetal or a salt thereof,ncharacterized in that an N-demethylerythromycin A or a saltnthereof is reacted with an isopropylating agent andnsubsequently treated under acidic conditions, and a methodnof producing a substantially pure crystal of an 8,9-anhydroerythromycinnA-6,9-hemiacetal derivative representednby formula (VI):n nwherein R 1 and R 2 , whether identical or not, represent annalkyl having 1 to 6 carbon atoms, an alkenyl having 2 to 6ncarbon atoms or an alkynyl having 2 to 6 carbon atoms; R 3 nrepresents hydrogen or a hydroxyl group; one of R 4 and R 5 nrepresents hydrogen and the other represents a hydroxylngroup, or R 4 and R 5 bind together to represent O=; R 6 nrepresents hydrogen or a hydroxyl group that may bensubstituted for; R 7 represents hydrogen or a hydroxylngroup; or a salt thereof, characterized in that a crudencrystal of said 8,9-anhydroerythromycin A-6,9-hemiacetalnderivative or a salt thereof is recrystallized as ansolvation product from hydrated isopropanol. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02102819-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6916792-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101619085-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101619085-B |
priorityDate | 1996-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.