abstract |
The invention relates an erythromycin derivative, belonging to the medicine technical field. The structure of the erythromycin derivative is shown in formula (I); wherein, a and e can be 0 or 1, b, c and d can be 0, 1, 2, or 3, but a, b, c, d and e can not be 0 at the same time. The invention also provides non-toxic salts of the derivative shown in the structural formula and hydrates thereof which are acceptable in pharmacy. The derivative has better antitumor activity and can be used as tumor cell proliferation inhibitor for preparing tumor drugs. |