abstract |
The utilization of mannosylglycerate as a stabilizer of enzymes and other cell components orncells, namely against heat, freezing, desiccation, lyophilization or repeated usage, is disclosed.nExamples with lactate dehydrogenase and alcohol dehydrogenase show that this compound is anbetter protecting agent than trehalose. This solute is produced in the hyperthermophilic archaean Pyrococcus furiosus , species of the genera Methanothermus and Thermococcus , and in thenthermophilic bacteria Rhodothermus marinus and Thermus thermophilus . A purificationnprocedure is disclosed. |