Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_692dc75829481c48c017b52f352e2bad |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-0023 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-00 |
filingDate |
1996-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c35e3ccd1a0f5d9d10c75f41c749f49d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65280fcffa3f57bab380f463a31d0f36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27eebabaee9b249f307218ae09b61707 |
publicationDate |
1997-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0769503-A2 |
titleOfInvention |
A heparin complex and medical device having such substance |
abstract |
A heparin complex having anticoagulation activity and being insoluble in blood is provided. The preferred complex comprises a cationic alkyldimethylammonium represented by formula (1):n wherein R 1 and R 2 are independently an alkyl or alkenyl group, each group is C 12 -C 24 when R 1 and R 2 are the same, the sum of the carbon atoms are 26-38 when R 1 and R 2 are different; and heparin. In this complex, reduction in the anticoagulation activity of the heparin by the formation of the complex is minimized, and ionic bonding of the heparin is quite stable. Dissolution of the cationic alkyldimethylammonium from the coating is also minimized. A medical device coated with such substance is also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8101196-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105194742-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1579879-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1579879-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2941249-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1120123-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0143791-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7056458-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6200588-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1057492-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6967003-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9127091-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6533766-B1 |
priorityDate |
1995-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |