| abstract |
The present invention provides pharmaceutically active compounds of formula In wherein n R 1 is -H, -OH, -O(C 1 -C 4 alkyl), -OCOC 6 H 5 , -OCO(C 1 -C 6 alkyl), or -OSO 2 (C 2 -C 6 alkyl); n R 2 is -H, -OH, -O(C 1 -C 4 alkyl), -OCOC 6 H 5 , -OCO(C 1 -C 6 alkyl), -OSO 2 (C 2 -C 6 alkyl), or halo; n R 3 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; n n is 2 or 3; and n z is -O- or -S-; nor a pharmaceutically acceptable salt thereof. n Further provided are pharmaceutical compositions of compounds of formula I. |