Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f2186a0cf271e2f283c8ff629951565 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate |
1995-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c53d4780f0358f242ba07214060f84f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45f92208451fd8cd0f279022056b9777 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_026f8efbaf74da71b9dafb427289e98f |
publicationDate |
1995-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0677533-A2 |
titleOfInvention |
Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof |
abstract |
Novel methods of obtaining autologous monoclonal antibodies (AMABs) to self-antigens or homologs thereof are disclosed. The method involves genetically engineering a host animal so that it does not biosynthesize at least one epitope of the self-antigen and utilizes the lack of self-tolerance of the host to the epitope to produce antibodies specific to the antigen. The invention also encompasses the AMABs produced by the methods. The invention further encompasses methods of isolating cells by using such AMABs that have specificity for a cell surface antigen. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8138314-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0198357-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932402-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007080404-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1606387-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8716449-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2336187-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007080404-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109475109-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8084020-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7026456-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1606387-A2 |
priorityDate |
1994-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |