Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4aefb306d25a71b08bb9414cdb92efb3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
filingDate |
1993-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_318fea6bb65c9597c7a97102f487006c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6910b50c1c7ccb852aa5ed88aaa94d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac590d404587929c81081a72c015febd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_580cb486592b48f82cbfd1804dabe535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fc3a476f7c83012b0e34af4822f73bf |
publicationDate |
1995-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0638573-A1 |
titleOfInvention |
Crystalline hydrates of cephalosporin and process for preparation thereof |
abstract |
The present invention relates to a crystalline hydrate of 7-[(Z)-2-(2-aminothiazole-4-yl)-2-(2-carboxylprop-2-oxyimino) acetamido]-3-(5-methyl-1,4,6-triaminopyrimidinium-2-yl) thiomethyl-3-cephem-4-carboxylate and a composition comprising said compound as an active ingredient. Also provided herein is a process for preparation of the compound which comprises the steps of: dissolving the compound in an amorphous form or its salt in an acidic or basic solution; adjusting the pH of the solution to a range from 1.5 to 5.5 by adding a basic or acidic solution; precipitating the compound in a crystalline form in the solution; and recovering said crystalline hydrate of the compound. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6034076-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9626209-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1227100-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2539348-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6887992-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1227100-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1447406-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2539348-A1 |
priorityDate |
1993-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |