http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0617973-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92c15547603b5c229a654d870a40e296 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09J4-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J4-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-06 |
filingDate | 1994-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_205e108ecbe859bbd31373942dcbd269 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f529d52be9b43ed0e0076df98c4800 |
publicationDate | 1994-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0617973-A1 |
titleOfInvention | Biocompatible monomer and polymer compositions |
abstract | A biocompatible monomer composition contains (A) at least one monomer of the formula: n n CHR=CXY n n n wherein X and Y are each strong electron withdrawing groups, and R is H or, provided that X and Y are both cyano groups, a C₁-C₄ alkyl group; and (B) an effective amount of at least one biocompatible agent effective to reduce active formaldehyde concentration levels, preferably a formaldehyde scavenger compound. The monomer is preferably an alpha-cyanoacrylate. The formaldehyde scavenger compound may be in microencapsulated or non-microencapsulated form. The composition can be applied to a variety of materials and is particularly suitable as in vivo tissue adhesive. A method of joining together in vivo two surfaces, e.g., body tissues, includes (a) applying to at least one of the surfaces a composition containing 1) at least one monomer, preferably an alpha-cyanoacrylate, which forms a polymer whose in vivo biodegradation produces formaldehyde; and 2) an effective amount of at least one biocompatible agent effective to reduce active formaldehyde concentration levels, preferably a formaldehyde scavenger; and (b) maintaining the surfaces in contact until the composition polymerizes. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2110370-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10259968-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006121977-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009158302-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009158302-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5550172-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7932305-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9187655-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006121977-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012245267-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9749436-A1 |
priorityDate | 1993-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 265.