| abstract |
This invention concerns systems for the release of active principles which are capable of releasing active principle(s) into an aqueous medium at a controlled rate. n More precisely, the invention concerns a monolithic system for the controlled release of active principles, consisting of:n a) at least one swelling layer containing one or more active principles, in a matrix of swellable, hydrophilic polymers; b) at least one erodible and/or soluble layer comprising excipients and/or water soluble polymers, possibly containing one or more active principles, either the same or different from those present in the layer a), the said erodible and/or soluble layer being in contact with the swelling layer(s) a). |