abstract |
Compounds of formula (I):n n wherein: R is an alkyl group; X is oxygen or sulphur; Y is hydrogen atom or -A-COOH, in which A is an alkylene group; Ar is aryl or substituted aryl group; and pharmaceutically acceptable salts and esters thereof, have use in the treatment or prophylaxis of diabetes, obesity, hyperlipaemia, hyperglycaemia, complications of diabetes, obesity-related hypertension and osteoporosis. |