| abstract |
Compounds of formulan n wherein Het isn n R₁ is a C₁-C₃ lower-alkyl; n R₂ and R₃ can each independently be hydrogen or fluorine; n R₄ is methyl or trifluoromethyl; nwith the proviso that when Het isn n R₁ is methyl and R₂ is fluorine; and when Het isn n R₁ is methyl, R₂ is 2-fluoro, R₃ is hydrogen and nR₄ is methyl; n or pharmaceutically acceptable acid addition salts thereof, are useful as antiviral agents, particularly against picornaviruses. |