abstract |
Improvements in a composition ensuring a supply of bioactive agent and method of application. The composition includes a bioactive agent, a hydrophilic polymer in an incompletely hydrated state, and a water-miscible solvent system. The agent and the polymer are dissolved in the solvent system to form a sprayable composition having a viscosity of less than 350 cP. When diluted with water, the viscosity of the composition increases until it exceeds 1000 cP in order to produce a retention coating on the application site, which improves the capacity for biological use of the agent. |