abstract |
The invention provides isolated nucleic acid molecules encoding human 5-HT1D receptors, isolated proteins which are human 5-HT1D receptors, vectors comprising isolated nucleic acid molecules encoding human 5-HT1D receptors, mammalian cells comprising said vectors, antibodies developed against human 5-HT1D receptors, nucleic acid probes used to detect the nucleic acid encoding human 5-HT1D receptors, oligonucleotides complementary to any sequence of a nucleic acid molecule encoding a human 5-HT1D receptor, pharmaceutical compounds relating to human 5-HT1D receptors, as well as transgenic animals expressing DNA encoding a normal 5-HT1D receptor or a mutant human 5-HT1D receptor . The invention also provides methods of determining ligand binding, expression detection, drug sorting and treatment using the human 5-HT1D receptor. |