| abstract |
Modified Beta Adrenergic Receptors having the amino acid residue in position 113 substituted by certain other amino acids have been synthesized. These modified receptors interact with novel ligands that do not react with the natural Asp 113 containing receptors. Transgenic animals containing this modified receptor will respond to novel ligands which will not interact with the normal receptor. n n RELATED APPLICATION n n The present application is a continuation-in-part of our copending U.S. Patent Application Serial No. 223,182, filed 22 July, 1988. |