abstract |
R¹ (C₂-C₁₀)-Alkyl Z Stickstoff X,Y unabhängig voneinander CR² L -CH₂- q Null oder 1 A Biphenylrest, der z.B. mit R¹⁵ substituiert ist R² Halogen oder Wasserstoff R¹⁵ SO₂-NH-CO-OR⁶ und R⁶ Phenyl, sind hochwirksame Antagonisten von Angiotensin-II-Rezeptoren.Azole derivative of general formula (I), where A, L, O, R 1, X, Y, Z and q have the meanings indicated, processes for their preparation, pharmaceutical preparations and the use of the compounds are described. Azole derivatives of the formula I where the symbols have, for example, the following meanings: R (C₂-C₁₀) -alkyl Z nitrogen X, Y independent of each other CR² L -CH₂- q Zero or 1 A Biphenyl, which is substituted for example with R¹⁵ R Halogen or hydrogen R¹⁵ SO₂-NH-CO-OR⁶ and R⁶ phenyl, are highly potent antagonists of angiotensin II receptors. |