abstract |
Composition intended to be used to curb hair loss and to induce and stimulate their growth, containing 2-amino-4 (or 2,4-dialkyl) pyrimidine oxide-3 derivatives and new compounds derived from alkyl- 2 amino-4 pyrimidine oxide-3.n n n Pharmaceutical or cosmetic composition intended to be used in tonic application to slow down hair loss and to induce or stimulate their growth, containing at least one compound of formula: or : R l denotes H, C l -C₈ alkyl; R₂ denotes C l -C₈ alkyl, NHR₃ where R₃ denotes H, -COOR₄ where R₄ denotes C l -C₄ alkyl; X denotes -OR₉ or -SR l0 ; R₅ and R₆ denote H, optionally substituted C 1 -C 12 alkyl, C₂ C 12 alkenyl, C₃ C 10 cycloalkyl, aralkyl or aryl or form with N a saturated or unsaturated heterocycle; R₉ denotes optionally substituted C 1 -C 12 alkyl, C₂ C 12 alkenyl, C₃ C 10 cycloalkyl, C₇ C 12 aralkyl, optionally substituted phenyl; R l0 is identical to R₉; Y denotes O or OSO₃ ⊖ ; as well as its cosmetically or pharmaceutically acceptable acid addition salts. |