| abstract |
The invention relates to salts formed between basic H 2 -receptor antagonists and a complex of zinc with a carboxylic acid selected from tartaric acid, citric acid and alkyl citric acids, and to solvates of such salts, excluding salts in which the basic H 2 -receptor antagonist is ranitidine. Examples of basic H 2 -receptor antagonists are cimetidine, famotidine, nizatidine and roxatidine. n The salts are useful in the treatment of gastrointestinal disorders, such as peptic ulcer disease and non-ulcer dyspepsia. |