Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7455 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745 |
filingDate |
1990-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfeccad8c8a9c1f2205539ebf9752e26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d23ed0a81457253168e2589e4bfe31f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b952376cd334b5c219a2696451e9da09 |
publicationDate |
1991-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0445304-A1 |
titleOfInvention |
Isolated, physiologically active human thrombomodulin polypeptide |
abstract |
An isolated polypeptide (type II polypeptide) comprising a physiologically active human thrombomodulin polypeptide which can promote the activation of protein C by thrombin, wherein the peptide chain has a sugar chain containing chondroitin and/or chondroitin sulfate. It can be isolated from a conventional culture medium containing, for example, a product of genetic expression of a human thrombomodulin polypeptide by recombinant DNA technology, and is excellent in anticoagulant, platelet agglutination inhibiting and thrombolytic activities. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5834028-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5574007-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0915340-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0474273-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0474273-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196625-B2 |
priorityDate |
1989-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |