abstract |
Process for the preparation of pearls based on a pharmaceutical active ingredient having an undefined crystallization point.n n n The active ingredient is mixed in the molten form with a pharmaceutical excipient favoring the solidification of the active ingredient, the passage of the molten mass is forced through a nozzle which undergoes a vibration, the beads are dropped into a tower against the current formed, we gather the pearls formed at the bottom of the tower. |