| abstract |
An azole derivative represented by the following formula (I):n wherein X is a nitrogen atom or CH, Y is an oxygen atom, a sulfur atom, an imino group, a methylimino group or a group represented by =N O-, Z is one or two halogen atoms, n stands for a number of 1 or 2, the wavy line means that stereochemistry of the double bond is either E or Z; or an acid adduct thereof. n They exhibit strong antifungal activities and are very useful in the therapy for fungus diseases. n Also disclosed is an antifungal drug containing said compound as an active ingredient. |