| abstract |
Compounds of formulawherein R is a phenyl group; a phenyl group mono- or disubstituted by halogen atoms, methyl, methoxy, nitro, or trifluoromethyl group; or a 2-, 3- or 4-pyridyl group; and pharmaceutically acceptable acid addition salts thereof.Compounds I are prepared by reacting N-substituted piperazineswith 1-(2',4'-dichioro-benzoyimetyl)-imidazole,optionally reducing thereafter the resulting enamines.Compounds I have antimycotic and antibacterial activities, higher than those of known comparison drugs. |