http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0385593-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 |
| filingDate | 1990-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04100137ff39e00f79aa6f445fd579e4 |
| publicationDate | 1990-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0385593-A1 |
| titleOfInvention | Phosphorus containing renin inhibitors |
| abstract | A renin inhibitor, useful in treating hypertension, of the formula:n or a pharmaceutically acceptable salt thereof, wherein R 1 isn n or X-Y-, where X is morpholino, N-methylpiperazino, piperidino, pyrrolidin-1-yl, pyrrolyl, 3- oxopyrrolidin-1-yl, imidazolyl, cis-4-hydroxycyclohexyl, trans-4-hydroxycyclohexyl, acetylalkyl having three to six carbon atoms, alkyl having one to three carbon atoms, 4-oxopiperidino, 4-oxocyclohexyl, alkoxy having one to five carbon atoms or 4-hydroxypiperidino and Y isn orn R 2 is hydrogen or methoxy; R 3 is alkyl having one to four carbon atoms, methoxyalkyl said alkyl having one to three carbon atoms, methythioalkyl said alkyl having one to three carbon atoms, hydroxymethyl, imidazol-4-ylmethyl, methylsulfonylmethyl, methylsulfinylmethyl or carbamylethyl; R 4 and R 5 when considered separately are each alkyl having one to three carbon atoms, benzyl, alkoxy having one to four carbon atoms, dimethylamino or hydroxy; and R 4 and R 5 when taken together are alkylene having four to six carbon atoms, alkylenedioxy having three to four carbon atoms or mono- or dimethylalkylenedioxy having four to six carbon atoms. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007117560-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007117560-A3 |
| priorityDate | 1989-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 312.