abstract |
The novel 2′,3′-dideoxynucleosides of which the sugar moiety is fluorinated at the 3′ position: 3′-fluoro-2,6-diaminopurine 2′,3′-dideoxyriboside; and 3′-fluoro-2′,3′-dideoxyguanosine, selectively inhibit the cytopathogenicity and replication of retroviruses (i.e. human immunodeficiency virus). |