Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-877 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-40 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57 |
filingDate |
1988-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_175d58bebf60e047692548e3b0e4d5a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_823f7dc16ce3e73029f18f8e9a3ff77a |
publicationDate |
1988-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0291055-A2 |
titleOfInvention |
Stable creatinamidinohydrolase mutants |
abstract |
A new creatinamidinohydrolase, in which alanine at position 109 of the amino acid sequence of the wild-type enzyme is replaced by valine and optionally one or more additional amino acids of the wild-type enzyme are mutated, is more stable than the wild-type enzyme and is therefore more suitable for reagents. For their production, recombinant DNA is expressed according to known genetic engineering methods in a suitable expression system, which contains a creatinamidinohydrolase gene which contains the deoxyribonucleotide T in position 326 of the natural gene instead of C. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6958231-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5043279-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2619123-A1 |
priorityDate |
1987-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |